hyperbili

Neurotoxicity Risk Factors

Table 1b: Risk factors that increase the neurotoxic effects of bilirubin

• Lower gestational age (<38 weeks)*
• Hypoalbuminemia (serum albumin <30 g/L)
• Suspected or diagnosed hemolytic conditions**
• Suspected or culture proven sepsis
• Significant hemodynamic and/or respiratory instability in the preceding 24 hours

*Gestational age is automatically incorporated when you select "GA at Birth" and does not need to be considered when choosing "Yes" or "No" for Risk Factors

**Hemolysis may be suspected based on a rapid rate of increase in TSB ≥5µmol/L/hr (within 24 hours after birth) or ≥3.5µmol/L/hr (beyond 24 hours after birth)